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  1. Heritability and Genome-wide Association Study of Vaccine-induced ...

    Apr 24, 2025 · Both genetic and non-genetic factors contribute to individual variation in the immune response to vaccination. Understanding how genetic background influences variation in both …

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  2. Immune response at a vaccine-challenge study using beagle dogs and ...

    Jan 1, 2023 · For assessment of immunity of the vaccine serum antibodies were detected before and after vaccination and challenge in three studies. The effects of the challenge were determined by a …

  3. Historically, beagles have been instrumental in the development of cardiovascular drugs, cancer treatments, and vaccines. Despite their utility, the ethical and biosafety implications of using beagles

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    • immune studies
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  4. Beagle PBMCs | Reliable immune cells for research

    Beagle PBMCs are genetically and immunologically similar to humans, making them ideal for studying immune responses, vaccine efficacy, and preclinical drug testing.

  5. Enhancing immune response, antioxidant capacity, and gut health in ...

    Jan 11, 2024 · The objective of the present study was to investigate the impact of COS-supplemented diets on the immune response, antioxidative capacity, hematology, serum biochemistry, and …

  6. Vaccination-Challenge Trials in Beagle Dogs Using Whole-Cell

    Jun 20, 2025 · A killed, whole-cell vaccine was produced to induce immunity in dogs against leptospirosis. The vaccine, containing serovar Copenhageni, was produced and administered to 12 …

  7. Evaluation of protective immune responses induced by DNA vaccines ...

    Sep 25, 2024 · In this study, the EgM123 antigen was selected for its well-documented immunogenic properties to develop a DNA vaccine aimed at combating E. granulosus infection in canines. The …

  8. Heritability and genome-wide association study of vaccine-induced ...

    Apr 30, 2024 · The objective of this study was to estimate the heritability of the antibody response to vaccination against viral and bacterial pathogens, and to identify genes driving variation of the …

  9. Dog leukocyte antigen genotyping across class I and class II genes in ...

    Jun 26, 2024 · The obtained data should facilitate the use of laboratory beagle dogs to investigate disease processes in various immune-related responses associated with a specific DLA type.

  10. Immune response at a vaccine-challenge study using beagle dogs and ...

    Nov 1, 2022 · For assessment of immunity of the vaccine serum antibodies were detected before and after vaccination and challenge in three studies. The effects of the challenge were determined by a …