Background Heart auscultation is a widely used and cost-effective clinical tool for detecting valvular heart disease (VHD), ...

Background Cancer survivors have an increased risk of heart failure, but this is balanced by the risk of death from other ...

Background Surgical ablation (SA) is a key treatment for atrial fibrillation (AF) patients undergoing heart surgery. However, direct comparisons between SA and non-mitral valve (non-MV) surgery alone ...

Background Chronic kidney disease is common in patients with coronary artery disease (CAD) and can significantly affect drug excretion and efficacy. This study focuses on the effects of modification ...

Background Restarting direct oral anticoagulants (DOACs) after a serious bleeding event in patients with atrial fibrillation (AF) presents a clinical dilemma, with limited evidence on the balance ...

Cardiovascular complications are increasingly recognised as a major driver of morbidity and early mortality in patients with sickle cell disease (SCD), yet they remain underdiagnosed and ...

Background Heterogeneity of heart failure with preserved ejection fraction (HFpEF) results in significant challenges for treatment development. Identifying and characterising distinct HFpEF ...

Congenitally corrected transposition of the great arteries (ccTGA) is a rare defect representing approximately 0.5% of all congenital heart disease. ccTGA is characterised by the combination of ...

The workup of cardiac disease in patients with autoimmune disorders The range of CV manifestations of rheumatological diseases are broad and include but are not restricted to coronary artery disease ...

The timing of aortic valve surgery is described for patients presenting with two conditions: aortic stenosis and chronic aortic regurgitation. Aortic stenosis may be caused by rheumatic disease, a ...