Detroit Lions prepare for high-stakes matchup against AFC East leaders Buffalo Bills as both teams eye playoff advancement in ...

These current Bills, winners of seven of their last eight games, have been one of the best teams in the NFL all season long. They handed the two-time reigning Super Bowl champion Kansas City Chiefs ...

However, the moniker actually fits this Week 15 showdown in Motown between the 10-3 Buffalo Bills and the 12-1 Detroit Lions.

The San Francisco 49ers hosting the Los Angeles Rams, a soft three-point favorite for San Francisco. The over-under, it has ...

Jayden Daniels and Caleb Williams are among UPI senior sports writer Alex Butler's five must-start fantasy football ...

Green Bay and Seattle played seven times over that span. Since the infamous 2014 NFC title game, the Packers have won five of ...

Tennessee is a 5-point home underdog in the Week 15 NFL odds against Cincinnati, and the Titans are one of seven home dogs ...

Detroit's defense is embracing the new nickname given to them by their head coach. Speaking to reporters, Jack Campbell seemed excited to discuss a moniker he felt encapsulated what the defense is ...

Key matchups, player performances, and insights on how Philadelphia can maintain its winning streak in Week 15 against ...

The Detroit Lions defense has incurred a ton of injuries this season, but no position has been hurt more than the linebacker ...

Another 3-2 against-the-spread week for us on our top five picks. Backing the Tennessee Titans was clearly a poor decision, ...

Playoff implications are on the line as the Rams face the 49ers, the Bills visit the Lions and the Eagles play host to the ...