Frontiers

Integrating single-cell RNA sequencing with spatial transcriptomics reveal the fibrosis-related genes in hepatocellular carcinoma

Background: Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality, with limited efficacy of current therapies in advanced cases. As a key risk factor for HCC, liver ...
IEEE

STINR: Deciphering Spatial Transcriptomics via Implicit Neural Representation

Abstract: Spatial transcriptomics (ST) are emerging technologies that reveal spatial distributions of gene expressions within tissues, serving as important ways to uncover biological insights. However ...
Frontiers

Single-nucleus and Spatial Transcriptomics Reveal Intestinal Cellular Heterogeneity, Differentiation, and Cell Communication Mechanisms in SAP-induced Intestinal Injury

The final, formatted version of the article will be published soon. Abstract Background Acute pancreatitis (AP) is a severe inflammatory disease that frequently causes multi-organ damage, with ...
IEEE

Revolutionizing Drug Discovery: Integrating Spatial Transcriptomics with Advanced Computer Vision Techniques

Abstract: Spatial transcriptomics has emerged as a transformative technology for mapping gene expression within tissue contexts, offering unprecedented insights into disease mechanisms. However, ...