Introduction: High levels of extracellular adenosine, highly abundant in the tumor microenvironment, promote immune suppression mainly through the A2AR expressed by tumor-infiltrating immune cells.

Spatial transcriptomics (ST) technologies reveal the spatial organization of gene expression in tissues, providing critical insights into development, neurobiology, and cancer. However, the high cost ...

Abstract: Deciphering cell-type composition is critical for charting single-cell spatial maps and cellular atlases of organisms. Most Spatial Transcriptomics (ST) data lack single-cell resolution, ...

Hi, I am trying to run sopa Baysor cell segmentation pipeline with 10x xenium data. I am using snakemake version 9.14.0, and sopa newest version. When i run ...

(MEMPHIS, Tenn. – December 3, 2025) Spatial transcriptomics provides a unique perspective on the genes that cells express and where those cells are located. However, the rapid growth of the technology ...

Neural stem cells (NSCs) hold significant potential in neural regenerative medicine, yet research faces multiple challenges such as cellular heterogeneity, unclear microenvironment interactions, and ...

A comprehensive review article titled “Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses,” published in Quantitative Biology, ...

Experiments were executed with PyTorch 2.1.0+cu121 on NVIDIA A40 with 46068MiB memory in linux environment. adata_utils file contains 4 functions, preprocess function selects highly variable genes ...