Gene-editing tools like CRISPR have unlocked new treatments for previously uncurable diseases. Now, researchers at the ...

Discover the innovative TECHNO platform for full-length gene humanisation, enhancing models for human gene function.

Humanized mouse models are essential for investigating human gene function; however, the complete replacement of mouse genes ...

A bacterial defense system called SPARDA employs kamikaze-like tactics to protect cells and could be useful in future ...

Understanding human gene function in living organisms has long been hampered by fundamental differences between species.

Understanding human gene function in living organisms has long been hampered by fundamental differences between species. Although mice share most ...

Infection with the pathogenic yeast fungus Candida auris (C. auris) can wreak havoc on the health of hospital patients and residents of nursing homes, especially those who are already weakened by ...

As he addressed an audience of virologists from China, Australia, and Singapore at October’s Pandemic Research Alliance Symposium, Wei Zhao introduced an eye-catching idea. The gene-editing technology ...

A one-time CRISPR infusion called CTX310 showed early, lasting drops in LDL and triglycerides in a first-in-human Phase 1 trial. House Republicans aren’t having any fun Billionaire’s heirs to pay $750 ...

Introduction: Human butyrylcholinesterase (hBChE) is a promising bioscavenger against organophosphorus (OP) nerve agents and pesticides. However, low homology-directed repair (HDR) efficiency in ...

In a 15-patient, Phase 1, first-in-human trial, a one-time CRISPR-Cas9 gene-editing therapy safely reduced LDL cholesterol and triglycerides in people with difficult-to-treat lipid disorders, ...