The NFC West playoff race heats up as the 49ers (6-7) and Rams (7-6) clash on Thursday Night Football. The Rams are riding a ...

When the Rams take on the 49ers on Thursday night, the veteran quarterback will try to set a personal milestone with another ...

San Francisco 49ers head coach Kyle Shanahan addressed reporters during a Monday conference call, a day after the team's dominant 38-13 victory over the Chicago Bears. He shared several injury updates ...

With Christian McCaffrey and Jordan Mason on injured reserve, Guerendo made his first NFL start against the Bears. If he ...

Breaking down all of the good and some of the bad from the 49ers’ much-needed blowout win over the Bears in Week 14.

Already missing five starters during the blowout loss to the Bills, San Francisco lost star running back Christian McCaffrey ...

San Francisco 49ers safety Talanoa Hufanga, defensive back Deommodore Lenoir and defensive lineman Jordan Elliott are set to ...

SportsLine's model simulated Chicago Bears vs. San Francisco 49ers 10,000 times and made its Week 14 NFL picks, predictions ...

It's the final week of byes and also the swan song for the regular season in some fantasy leagues, making for an intriguing ...

San Francisco 49ers running back Christian McCaffrey was placed on injured reserve and is likely out for the season after suffering a PCL injury in Week 13 agai ...

The San Francisco 49ers are facing another setback as defensive lineman Nick Bosa is officially out for Sunday's game.

The San Francisco 49ers are reportedly expected to lean on rookie running back Isaac Guerendo for the remainder of the 2024 ...