The San Francisco 49ers defense struggled some against the Tennessee Titans, but their offense had a huge day to mark the team’s fourth win in a row.

The Pro Bowl voting just ended for fans, and in a week or two, the teams will be announced. The San Francisco 49ers had a few players crack the top ten in fan voting, but that is only ⅓ of the vote. Which 49ers players may get the honour?

The 49ers can clinch a playoff berth in Week 16 with a win over the Colts — or with help before kickoff. Here's how San Francisco gets in.

San Francisco 49ers quarterback Brock Purdy joins NFL Network's "Inside Training Camp Live" to provide a state of the team's offense including chemistry with the wide receiver corps and better understanding head coach Kyle Shanahan's system entering year four.

The Indianapolis Colts host the San Francisco 49ers on " Monday Night Football " in NFL Week 16 action. Both teams are watching injuries in the wake of Week 15 games.

The 49ers will look to carry that momentum into Week 16 when they hit the road for a matchup against the Indianapolis Colts. San Francisco is set to face veteran quarterback Philip Rivers, who recently came out of retirement to replace Daniel Jones after the Colts' starter suffered a season-ending Achilles injury.

Highlighting the San Francisco 49ers interns, their career paths, roles within the organization, and advice for aspiring professionals.

The 49ers have brought in a fourth quarterback. San Francisco announced on Wednesday that the club has signed Adrian Martinez to its practice squad. Martinez has bounced between the 49ers practice squad and 53-man roster this season before a quick stint last week with the Jets’ practice squad.

Need to know. Brock off a bye. 49ers quarterback Brock Purdy has played two games off a bye in his career, and he has been nearly perfect in both. In those two g

Winning 37-24 against the Tennessee Titans required a bunch of pivotal plays for the San Francisco 49ers. The game would've been closer had it not been for that