The Indianapolis Colts made several big additions to their roster this offseason, but they lost some key free agents as well.

We've spent a lot of time throughout this offseason highlighting teams' efforts to reshape their rosters so they're in a ...

The Indianapolis Colts have had a busy offseason filled with new signings and a few key losses. Some of those departures ...

The Dallas Cowboys ' run game last season left a lot to be desired, and it wasn't until Rico Dowdle was handed the starting ...

The Kansas City Chiefs lost the Super Bowl to the Philadelphia Eagles in February, yet that loss wasn't the most impactful for the roster. Yes, losing the Super ...

Throughout the Tennessee Titans' offseason, the team made some worthwhile touchups on both sides of the ball to give this group a much better outlook than their ...

The San Francisco 49ers had a clear reason in parting with Deebo Samuel earlier in the offseason, but will his departure ...

Obviously the Super Bowl champion carries weight, but the resume looks better when beating a divisional opponent deep in the ...

So, who was the 49ers' most significant offseason loss? According to CBS Sports' Jared Dubin, it's wide receiver Deebo Samuel—a player he believes will be extremely difficult to replace.

Prediction: Win (5-4). It's a big game between two AFC East teams looking to improve in 2025... but home on a Thursday is an ...