Animal studies often fail to predict human tissue responses to new drugs or newly developed therapies. Besides generating ...

As a researcher, I still remember the discomfort I felt every time I had to sacrifice laboratory animals for an experiment.

Plant immunity is largely initiated at the cellular level, with each cell capable of autonomous detection and response, while ...

Cell- and animal-based models of bone formation reveal novel mechanisms involved in the cartilage-to-bone phenotype ...

An AI model that screens ionizable lipids by 3D conformation identified a candidate 14.8 times more efficient than current ...

Changing the types of fat in your diet might help preserve cognitive health as you age. A new cohort study links substituting saturated animal fats with plant-based vegetable oils to a lower risk of ...

The FDA has released draft guidance that aims to clear up how drug developers can use alternative testing – but that doesn’t ...

On the flipside, if telomeres are too long, it can also spell trouble because cancer cells require long telomeres to become longer lived, ‘immortal,’” says Mia Levine, associate professor of biology ...

Engineered tissue could eventually be used for children born with gaps in their alimentary canal, or for adults whose muscles ...

Scientists from Great Ormond Street Hospital (GOSH) and University College London (UCL) have created the first lab‑grown esophagus—the food pipe—shown to safely replace a full section of the organ and ...

The FDA’s recent announcement to reduce, and in some cases replace, animal testing for monoclonal antibodies and other therapeutics represents one of the most consequential regulatory developments in ...

A common oral bacterium tied to gum disease may help spark and fuel breast cancer, according to new research. Scientists discovered it can travel through the bloodstream to breast tissue, where it ...