Medicines come from chemical reactions, and better chemical reactions lead to better medicines. Yet, the most popular reaction used in drug discovery, called the amide coupling, makes an inherently ...

Linking molecular components through amide bonds is one of the most important reactions in research and the chemical industry. Scientists have now introduced a new type of reaction for making amide ...

It’s dinnertime, and the only food in your house is a can of beans and a box of spaghetti. What can you make? A new mapping method that combines known reactants in unfamiliar ways can help organic ...

DESPITE THEIR FUNDAMENTAL ROLE in chemical and biochemical systems, amides are tough to make. Routes to this functional group usually employ toxic reagents, such as thionyl chloride; require corrosive ...

Novel, atom-efficient routes to amides from esters and carboxylic acids for more sustainable manufacturing. It is well known that amide-formation chemistry can be inefficient and warrants further ...