Adding vancomycin to beta-lactam prophylaxis with cefazolin did not help prevent surgical-site infections in patients undergoing arthroplasty mostly for the knees or hips, a randomized trial showed.

BALTIMORE -- There was no benefit with a longer- versus shorter-duration prophylactic antibiotic regimen in reducing surgical site infections after endoprosthetic reconstruction for lower-extremity ...

A new study found substantial variability in the use and appropriateness of surgical antibiotic prophylaxis for commonly performed operations at children's hospitals in the United States. A new study ...

Objective. To evaluate the effectiveness of an intervention based on training and the use of a protocol with an automatic stop of antimicrobial prophylaxis to improve hospital compliance with surgical ...

Delivering microdose incision-site injections of clindamycin significantly reduced the rate of surgical site infections (SSIs) in skin cancer surgery. However, prophylaxis with flucloxacillin did not ...

The safety and efficacy of surgical procedures and immunosuppressive chemotherapy may be threatened by increasing antibiotic resistance, according to a new analysis. In both settings, patients ...

Antibiotic prophylaxis regimens are becoming less effective at preventing surgical site infections following colorectal surgery, researchers at the Center for Disease Dynamics, Economics & Policy and ...

This week The Lancet Infectious Diseases journal published the strongest evidence to date that increasing antibiotic resistance could have disastrous consequences for patients undergoing surgery or ...

This is a preview. Log in through your library . Abstract Perioperative prophylaxis accounts for a substantial proportion of antibiotic use in acute-care hospitals. There is clinical evidence of its ...

Surgical site infection (SSI) is a common complication of adult and pediatric surgery. Appropriate use of perioperative surgical antibiotic prophylaxis (AP) can help to minimize the incidence of SSI ...