The nuclear pore complex (NPC) is an essential, highly dynamic macromolecular assembly embedded in the nuclear envelope that orchestrates the precise exchange of proteins, RNA and other macromolecules ...

The center of the nuclear pore complex with highly dynamic FG repeat filaments wiggling. (Credit: Lim lab) The nuclear pore complex (NPC) is an active ...

An international study led by the University of Basel has discovered that nuclear pore complexes – tiny gateways in the ...

If the cell nucleus is like a bank for DNA, nuclear pores are the security doors around its perimeter. Yet more security doors aren't necessarily better: some cancer cells contain a dramatic excess of ...

Researchers have found that the stability of a protein next to its nuclear localization signal sequence impacts the rate of its entry into the nucleus. Recent research from The Francis Crick Institute ...

Proteins are most well-known for their intricate structures. The α-helices and β-sheets that form from interactions between sidechains create distinct shapes that, along with the specific amino acid ...