WITH our present knowledge of enzyme processes any conception of their mechanism must be essentially highly speculative. In the work under notice the author makes no claim to deal comprehensively with ...

High-resolution structures explain the mechanism of human PNPase and provide insights into mutations causing hereditary ...

Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterial pathogen that is often associated with healthcare settings but can cause serious infections in anyone. These illnesses are difficult ...

Sir2, an enzyme belonging to sirtuins, has been shown to be involved in the deacetylation of proteins. Researchers from the Institute of Science Tokyo reveal that a tandem allosteric effect of ...

A breakthrough advance has been made by trapping an intermediate in the mechanism of enzymes called heme peroxidases and determining its structure using a beam of neutrons from the heart of a nuclear ...

Researchers from the Cluster of Excellence Balance of the Microverse at the University of Jena and the Leibniz-HKI, together ...

An international research team has published a study in the journal The FEBS Journal that significantly advances the knowledge of a rare hereditary metabolic disease: classical homocystinuria. The ...

A fungicide commonly used by the agricultural industry to protect grains, fruit and vegetables from mold damage seems to kill fungi by a previously uncharacterized mechanism that delivers a metabolic ...

BUFFALO, N.Y. — In the human body, proteins called enzymes help speed up chemical reactions that are vital for life. After you eat, enzymes help your body break down food and obtain energy. Enzymes ...

Cravatt’s strategy for ferreting out new inhibitors for multiple enzymes simultaneously is a good example “of how a strong understanding of enzyme mechanisms can serve as a starting point for studies ...

Researchers at Helmholtz Munich, the Technical University of Munich and the LMU University Hospital Munich uncovered a ...