Credit: Getty Images. The comparative efficacy of these therapies has been extended to patients with stage 3 chronic kidney disease, a common comorbidity in gout. Allopurinol and febuxostat are ...

Matched cohort studies revealed infrequent adverse events (AEs) with either treatment, but the number needed to harm for any AE was more than three times higher with colchicine vs NSAIDs. The ...

Man on bed with pillow embrace foot with painful swollen gout inflammation Researchers compared the time to complete resolution of acute gout flare between early and late allopurinol initiation. Among ...

What is allopurinol used for? Allopurinol is commonly used to treat gout, which is a form of arthritis caused by too much uric acid in your blood and joints. Allopurinol may also be used to lower your ...

Gout flares are less frequent when serum urate levels are below 6 mg/dL after the first year of urate-lowering therapy. Gout flares are less frequent when serum urate (SU) levels are below 6 mg/dL ...

Delaying initiation of ULT during gout flares had no impact on flare severity, duration or recurrence risk. Patient preference and other individualized factors can determine when to start ULT.

Patients with gout who experienced a heart attack or stroke were twice as likely to have experienced a gout flare within the past 60 days compared with patients with gout who did not experience either ...

Credit: Shutterstock. The investigational drug AR882 appeared more effective and safer than allopurinol monotherapy in a phase 2 trial. A novel selective URAT1 inhibitor, AR882, further reduces serum ...

In a phase 2 trial, firsekibart — an IL-1 beta antibody — outperforms colchicine in preventing acute gout flares over 12 ...

Experts at the University of Nottingham, in collaboration with experts at Keele University, have found that the risk of heart attacks and strokes temporarily increases in the four months after a gout ...