Transcription errors occur during the process of copying genetic information from DNA to RNA, one of the key steps in gene expression.

Every living cell transcribes DNA into RNA. This process begins when an enzyme called RNA polymerase (RNAP) clamps onto DNA. Within a few hundred milliseconds, the DNA double helix unwinds to form ...

A detailed picture of what happens when DNA transcription is paused early in the process has been obtained by structural biologists at RIKEN. This could inform the development of new therapies.

In 1957, just four years after Francis Crick and other scientists solved the riddle of DNA’s structure—the now famous double ...

How chromatin responds to transcription-blocking DNA lesions is unclear. This study reveals that RNA polymerase II (RNAPII) ...

Pressing pause on DNA transcription What happens on the atomic scale when DNA transcription is paused has been unveiled for the first time Figure 1: An illustration showing RNA polymerase II (silver ...

New York University chemists have employed a computer simulation whose results have enhanced scientific understanding of the DNA transcription process. The study, funded by the National Institutes ...

A cell protein previously believed only to provide a scaffolding for DNA has also been shown to directly influence DNA transcription into RNA – the first step of the process by which an organism ...

DNA-binding transcription factor activity (229 of 1813 negatively correlated genes) was identified as one of the enriched categories of interest to the current work.

Aug 12, 2025 Pressing pause on DNA transcription What happens on the atomic scale when DNA transcription is paused has been unveiled for the first time. (Nanowerk News) A detailed picture of what ...