3D cell culture is the future of drug discovery and disease research. Scientists have relied on 2D cell culture and animal models for many years, but these models often fail to accurately replicate ...

Traditional 2D cell cultures can’t replicate the complexity of real tissues — resulting in limited insights and poor clinical translatability. In this new eBook, discover how integrating 3D cell ...

However, this simplicity is also a disadvantage: The isolated and static environment of the cells is not representative of the complex, dynamic, and interactive environment of cells in the body, thus ...

Cell transfection has been a transformative tool for understanding cellular function. Accurately measuring transfection efficiency is paramount for 2D cell culture studies. However, traditional ...

Figure 3. Design space visualization of the conditions that were tested in 2D cell culture. Replicates of the central formulation were included to investigate inherent biological variation.

A cell line was subsequently generated from that sample which was capable of being expanded in 2D culture.

Designed to address the limitations of traditional 2D cell culture systems, these scaffolds offer researchers a biomimetic microenvironment that enhances cellular behavior studies, drug discovery ...

Neurons in this system were more active than those in 2D cell culture. As reported January 14 in Neuron, scientists led by first author Emmy Li, now at Stanford University, California, and Martin ...