Although significant advances have been made in the pharmacologic and device-based treatment of HF, our understanding of the full range of the signaling and genomic mechanisms involved in HF ...

The addition of β-adrenergic antagonists to the treatment regimen for heart failure has validated the neurohormonal hypothesis and provided much-improved outcomes. This benefit had been in question ...

Noradrenaline is a neuromodulator secreted in the brain depending on behavioral context and physiological states of animal, influencing a wide range of physiological functions by modulating brain ...

The benefits of angiotensin-converting–enzyme inhibitors and beta-blockers may be smaller in black patients than in patients of other races, but it is unknown whether race influences the response to ...

A new study finds that α 2-adrenergic agonists may be of benefit and have fewer side effects than stimulant medications for the treatment of attention deficit/hyperactivity disorder (ADHD) in ...

CuraSen Therapeutics has commenced its Phase IIa proof-of-concept trial of CuraAX (CST-3056) with dosing of the first patient ...

Recent clinical studies have suggested that phenylacetylglutamine (PAGln), a novel gut microbial metabolite, can mechanistically modulate patients' risk of developing cardiovascular disease (CVD) and ...

Researchers in Japan have discovered that the adrenergic nervous system controls when white blood cells circulate through the body, boosting the immune response by retaining T and B cells in lymph ...

An overdose happens when you take too much of a drug. Whether intentional or accidental, drug overdoses can be life-threatening. Adrenergic bronchodilators overdose is when a person takes too much of ...