University scientists have identified a gene responsible for initiating the normal development of tooth roots in mammals. Researchers made this discovery by creating a mouse lacking the gene ...

The alveolar bone is a specialized mineralized structure surrounding the tooth root, which plays a crucial role in the lifelong functionality of the tooth. The alveolar bone is an essential component ...

Tooth root development relies on precise coordination of cellular signals, yet the underlying mechanisms remain unclear. Researchers have uncovered how two proteins, Gli2 and Gli3, work together to ...

BUFFALO, N.Y. -- University at Buffalo scientists have identified a gene responsible for initiating the normal development of tooth roots in mammals. Researchers made this discovery by creating a ...

The tooth root is a critical component of the tooth, embedded in the socket and connected to the surrounding alveolar bone through the periodontal ligament 1. The tooth root transmits mechanical ...

Schematic diagram illustrating how Gli2 and Gli3 regulate Acvr2b-mediated TGF-β/SMAD signaling to control proliferation and differentiation of dental mesenchymal progenitor cells during tooth root ...

Two distinct stem cell lineages that drive tooth root and alveolar bone formation have been identified by researchers from Science Tokyo. Using genetically modified mice and lineage-tracing techniques ...

However, the outer layer of HERS extended without the root, and the mutant molars finally erupted. The periodontal tissues invaded extensively into the dental pulp. These results indicate that there ...

Scientists are uncovering a surprising link between hidden tooth infections and blood sugar problems. Deep infections around tooth roots can create chronic inflammation that spreads through the body ...