The human genome has to be carefully organized so it will fit inside of the nuclei of cells, while also remaining accessible ...

DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave.

The results of this collaborative project overturn some conventional wisdom about how the DNA repair process works. DNA is often likened to a blueprint. The particular sequence of As, Cs, Gs, and Ts ...

Most cases of localized or pre-metastatic prostate cancer can be cured by surgically removing the cancerous tissue or treating with radiotherapy. However, this is not true for aggressive metastatic ...

The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a UCL-led research team. DNA is widely accepted to be formed of two strands that wind around one ...

Scientists have created an unprecedented 3-dimensional structural model of a key molecular "machine" known as the BAF complex, which modifies DNA architecture and is frequently mutated in cancer and ...

Cockayne syndrome (CS) is a rare disease that causes short stature, premature aging (progeria), severe photosensitivity, and moderate to severe learning delay. A new study by researchers from the ...