Jellyfish, sea sponges, amoebas and other animals on the early branches of the tree of life defy conventional aging. A new study reveals diversity of proteins called sirtuins in these animals compared ...

Researchers found that the gene sirtuin 6 (SIRT6) is responsible for more efficient DNA repair in species with longer lifespans. The research illuminates new targets for anti-aging interventions and ...

A new research paper titled "Sirtuin 6 activation rescues the age-related decline in DNA damage repair in primary human chondrocytes" has been published in Aging. While advanced age is widely ...

Mammals convert the energy stored in adipose (fat) tissue into heat via a process known as thermogenesis. This process is regulated by a family of signaling proteins called sirtuins. A recent study by ...

Franklin H. Epstein, M.D., served the New England Journal of Medicine for more than 20 years. A keen clinician, accomplished researcher, and outstanding teacher, Dr. Epstein was Chair and Professor of ...

Cellular damage due to stress is an important factor in aging processes. It is, thus, amazing that starving, which is a stress factor per se, decelerates ageing processes and extends the lifespan of ...

LONDON, PHILADELPHIA AND CAMBRIDGE, Mass., April 22 -- GlaxoSmithKline and Sirtris Pharmaceuticals Incorporated announced today that they have entered into a definitive agreement pursuant to which ...