Senataxin (SETX) is an RNA/DNA helicase which catalyzes the resolution of R- loops, inherent byproducts of transcription consisting of an RNA:DNA hybrid and a displaced single-stranded DNA. Gain or ...
The alternative text for this image may have been generated using AI. Fig. 3: Long-range R-loop dynamics are governed by the 6 bp periodicity of the crRNA–target strand hybrid. The alternative text ...
Dysregulated R-loops can cause stalled replication forks and telomere instability. However, how R-loops are recognized and regulated, is still not well understood, particularly at telomeres. In a new ...
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