Protein glycosylation is a fundamental biological process that regulates various cellular functions, yet its study has been hampered by the complexity and low abundance of glycoproteins. In a ...

The host cell system is a critical determinant of recombinant protein quality and yield, with direct influence on protein folding and post-translational modification factors that shape the ...

At the University of Oxford, scientists have developed a nanopore technology that can identify three different post-translational modifications (PTMs) in individual proteins, even deep within long ...

Protein drugs feature significant advantages over small molecule therapeutics, including low toxicity, high specificity, and development speed. However, the quality control requirements are ...

Kidney diseases affect nearly 700 million people worldwide and are a growing cause of mortality and health care costs. Chronic kidney disease (CKD) alone contributes to over 1.2 million deaths ...

While the central dogma of molecular biology outlines the linear flow of genetic information from DNA to RNA to proteins (black lines), glycomics introduces a “3rd code of life”—glycans—that operates ...