Therefore, novel methods are needed for fast and easy diagnosis of PML–RARA positive APL, without subjective interpretation steps. We have developed a new antibody-based flow cytometric immunobead ...

The promyelocytic leukaemia (PML) protein controls multiple tumour suppressive functions and is downregulated in diverse types of human cancers through incompletely characterized post-translational ...

Deletions of p15 and/or p16 genes as a poor-prognosis factor in adult T-cell leukemia. To examine, in newly diagnosed patients with acute promyelocytic leukemia (APL), the prognostic significance of ...

Medicines that reshape or tamp down immune responses may be life-changing for patients with cancer and autoimmune disorders, but in some cases they can awaken a dormant virus and unleash a deadly ...