Understanding the delicate balance between nucleophilicity and electrophilicity is fundamental to rationalising reaction mechanisms in organic chemistry. Nucleophilic reactivity describes a molecule’s ...

A new halide addition reaction represents a means by which halides can be incorporated into biomolecules. The reaction was discovered by chemistry professors Charles L. Perrin and Joseph M. O'Connor ...

A new reaction that uses an atypical starting material to create amide linkages could make it easier to prepare peptides and other amide-containing compounds that have been difficult to make until now ...