The mouse is being widely used as a model organism in microarray studies, yet little is known about the range of normal physiological variance in gene expression in complex systems in vivo. In the ...

Genetic factor analysis uses genome-wide association summary statistics to identify shared polygenic factors underlying patterns of cross-trait genetic associations, while automatically determining ...

Genetic canalization describes the capacity of developmental systems to produce consistent phenotypes despite genetic mutations or environmental fluctuations. This robustness is achieved through ...

Blood samples are often used to evaluate gene expression in people. But those samples only provide a snapshot of gene activity at one moment in time. This point has been emphasized by a recent paper ...

The genes we possess not only determine the color of our eyes and hair and how our bodies grow, they might also influence the changes that occur in tumors when we develop cancer. A study by ...