MIT scientists have developed a microfluidic chip that mimics the neuromuscular connections that exist at the junction between neurons and the muscles. These junctions are often involved in various ...

A team of neuroscientists report on a new high-pressure flash-freeze technique that allows a more representative imaging of protein placement in and around synaptic neurotransmitter vesicles. The ...

After nerve injury, the protein complex mTORC1 takes over an important function in skeletal muscle to maintain the neuromuscular junction, the synapse between the nerve and muscle fiber. Researchers ...

UNC School of Medicine researchers have led an international clinical trial of patients with generalized myasthenia gravis, finding the therapy is safe and effective across all subtypes.

A SINGLE muscle fibre with its nerve supply (Fig. 1) has been dissected from the M. adductor longus of the frog (Hyla aurea). This preparation survives for as long as twenty–four hours at a ...

Modern tissue engineering developed at the University of Michigan could improve the function of prosthetic hands and possibly restore the sense of touch for injured patients. Researchers will present ...

MIT engineers have developed a microfluidic device that replicates the neuromuscular junction — the vital connection where nerve meets muscle. The device, about the size of a U.S. quarter, contains a ...

IF a foreign motor nerve is connected to a normally innervated muscle, the nerve fibres grow into it but do not establish intimate contact with muscle fibres, and are unable to transmit impulses to ...

James F. Howard Jr, MD, professor of neurology at the University of North Carolina at Chapel Hill, explains how nerve and muscle signaling in the neuromuscular junction go awry in myasthenia gravis.

What are the symptoms of the disease? It usually presents as fatiguing weakness of "proximal" muscles such as shoulders, thighs, hips. There are also cases of double vision, droopy eyelids and even ...

After nerve injury, the protein complex mTORC1 takes over an important function in skeletal muscle to maintain the neuromuscular junction, the synapse between the nerve and muscle fiber. Researchers ...

When nerve cells excite muscle fibers to flex, getting synaptic proteins and components into the right place can mean the difference between feats of strength or lapses of drowsy lethargy. Several ...