Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center for Cancer Biology and ...

This review explains how glucose scarcity, lipid disruption, amino acid deprivation, and toxic metabolites weaken CAR-T cells ...

The field of nutrition science increasingly recognizes the role of dietary bioactives, non-nutrient compounds in foods such as polyphenols, carotenoids, ...

While modern life includes many conveniences, humans are still incessantly exposed to a variety of metabolic stresses we have ...

Transcriptomic phenotyping offers mechanistic insight into adipocyte biology and metabolic disease. A signature of adipocyte ...

AMP-activated protein kinase (AMPK) plays a central role in maintaining energy balance in cells, especially under energy stress. While upstream activation by the kinase LKB1 is well recognized, the ...

Avi Flamholz leverages computational tools and microbial biochemistry to improve climate models and provide novel engineering ...