Meta-analysis is an objective examination of published data from many studies of the same research topic identified through a literature search. Through the use of rigorous statistical methods, it can ...

At first glance, the results of a recent meta-analysis published in JAMA Pediatrics would indicate immediately operating on a child is the most effective treatment for uncomplicated acute appendicitis ...

This manuscript makes a valuable contribution to the concept of fragility of meta-analyses via the so-called 'ellipse of insignificance for meta-analyses' (EOIMETA). The strength of evidence is solid, ...