Though the chemical mechanisms of many enzymes have been elucidated, the mechanisms by which specificity and rate acceleration are achieved remain less explored. A new study suggests that physically ...

Enzyme mechanisms of catalysis play many important roles in the functioning of a healthy body. An enzyme may exist as a multi-subunit complex or it may be associated with a cofactor such as adenosine ...

Photodynamic therapy (PDT), characterized by its non-invasive nature and precise spatiotemporal selectivity, has garnered considerable attention for its applications in tumor and anti-infection ...

Scientists observed the characteristics of a single enzyme inside a nanopore. This revealed that the enzyme can exist in four different folded states, or conformers, that play an active role in the ...

Enzymes accelerate reactions by helping to lower the activation energy needed to start them. But how enzymes achieve this has been the subject of intense debate. A research team from Texas and China ...

High-resolution structures explain the mechanism of human PNPase and provide insights into mutations causing hereditary ...

The enzymes found in living organisms have impressive catalytic power. Thanks to enzymes, the chemical reactions that sustain life happen millions of times faster than they would occur without them.

Researchers demonstrated enzyme-like heterogeneous catalysis for the first time. They developed a highly active heterogeneous TiO2 photocatalyst incorporated with many single copper atoms. They used ...

My laboratory is interested in novel mechanisms of enzyme catalysis, enzyme regulation and designing self-assembling proteins. Our current research projects focus on enzymes that catalyze ...