The question of putative mechanisms of action continues to haunt psychopharmacology. Put simply, we know these drugs work, but we have very little idea how. We make guesses based on the neurochemical ...
Conventional cancer drugs work by triggering apoptosis, that is programmed cell death, in tumor cells. However, tumor cells have the ability to develop strategies to escape apoptosis, rendering the ...
Gabriel Schwartz, MSN, NP, explains how mechanisms of action determine the safety of systemic treatments in metastatic ...
BALLERUP, Denmark--(BUSINESS WIRE)--NOT FOR UK USE – NOT INTENDED FOR UK MEDIA LEO Pharma A/S, a global leader in medical dermatology, today announced positive results from the Phase 2a Mechanism of ...
Blarcamesine, Aricept, and most probably simufilam are sigma-1 receptor agonists. Sigma-1 receptor agonists often produce temporary improvements in cognition for those with mild cognitive impairment ...
Distinguishing Unexpected Results From Unexpected Mechanisms of Action in Evaluating Non-Obviousness
Many inventions build on or combine previously known elements, requiring the Patent Office and courts to determine which combinations of, or improvement on, previously known elements are entitled to ...
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