Since the start of the COVID-19 pandemic, a class of corticosteroids called glucocorticoids (GCs) have become established as one of the main treatment options, especially for severe cases, thanks to ...

Patrick Burnett, MD, PhD, FAAD, chief medical officer of Arcutis Biotherapeutics, discusses the mechanism of action for roflumilast cream, the only phosphodiesterase-4 inhibitor approved by the FDA ...

Vamorolone (Agamree) is a first-in-class corticosteroid to treat Duchenne muscular dystrophy (DMD) in patients 2 years and older. Migvis Monduy, MD, pediatric neurologist and neuromuscular specialist ...

Used clinically since the 1920s, corticosteroids interrupt multiple steps in immune activation because of the ubiquitous expression of corticosteroid receptors. Corticosteroids inhibit antigen ...

Corticosteroid inhalers are a common treatment for asthma, but strangely, patients with severe asthma don’t seem to respond well to it. In a new study, scientists have identified a mechanism that ...

The question of putative mechanisms of action continues to haunt psychopharmacology. Put simply, we know these drugs work, but we have very little idea how. We make guesses based on the neurochemical ...

Active ingredient: Ciclesonide 80 µg/inhalation, 160 µg/inhalation; metered-dose inhaler. Indication: Maintenance treatment of asthma as prophylactic therapy in patients >12 years of age. Pharmacology ...