Novel Treatment Targets in Sarcoma: More Than Just the GIST MYC has proven to be a highly potent oncoprotein when it is overexpressed, but is also a pleiotropic transcription factor essential for ...
Second, the structure of the Myc protein itself does not have preferred binding pocket for traditional drug modalities. Myc protein lacks the catalytic clefts, and thus, has no feasible or effective ...
Show More From the Department of Cell & Tissue Biology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA; the Department of Cell & Tissue ...
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