Kinetin is shown to increase substantially the water permeability of liposomes composed of several types of phosphatidylcholines including the natural phospholipids egg lecithin and asolectin and the ...

Researchers at the Tokyo Institute of Technology say they have developed a computational method based on large-scale molecular dynamics simulations to predict the cell-membrane permeability of cyclic ...

Amyloid-β, the peptide that forms the hallmark plaques of Alzheimer disease, can exist in a variety of forms, including monomers, soluble oligomers, and fully fledged fibrils. The oligomers, or ...

Lipid bilayers in mammalian membranes can have a more asymmetric composition than previously thought, new research shows. This lipid abundance asymmetry is enabled by the unique properties of ...

Protein-lipid complexes in apolar solvents reassemble into large bilayer protein-lipid vesicles (PLVs) with diameters of several micrometers. PLVs form spontaneously upon hydration of the ...

Scientists have developed a computational method based on large-scale molecular dynamics simulations to predict the cell-membrane permeability of cyclic peptides using a supercomputer. Their protocol ...