According to researchers, noninvasive urinary assessments of kidney tubule health can identify risk of CKD progression beyond eGFR and albuminuria. Patients with chronic kidney disease (CKD) ...

aProximate TM is an advanced in vitro model of kidney proximal tubule cells (PTCs) that closely mimics physiological conditions. Derived from fresh human kidney tissue, aProximate TM PTCs are cultured ...

In videos created by the Hughes Lab to visualize the process, adjacent nephrons form one after the other, as if they were following a beat. “It’s still a hypothesis,” adds Hughes, “but we think that ...

Using measures of kidney function and biomarkers to look at kidney tubule damage, this study showed that use of NSAIDS for pain in older ambulatory adults did not lead to kidney injury or decrease in ...

Kidney failure is a lifelong burden in hundreds of thousands of people who need to be treated either by dialysis or a kidney transplant. Both procedures significantly increase the cost of healthcare ...

Using human iPSC-derived kidney organoids, researchers showed that NPHP1 deficiency triggers abnormal Hippo signaling that ...

Explore the fibrosis mechanism in NPHP and how blocking cellular pathways can reduce kidney scarring in children.

In the UK, more than 10 per cent of the population is estimated to have some stage of chronic kidney disease and more than 600,000 people develop some form of acute kidney injury – when the kidneys ...

Researches made major strides toward the creation of artificial kidney tissue by demonstrating an undiscovered mechanism behind kidney development and a novel technique for culturing kidney cells, ...