The parametric estimation procedure to predict long-term efficacy on survival from publication data of clinical trials for metastatic colorectal cancer (mCRC). This is an ASCO Meeting Abstract from ...
If the prime consequence of CD95 activation is to induce apoptosis, one would expect tumor cells to silence the pathway. Indeed, caspase-8 mutations are found in a small subset (~4%) of colon tumors, ...
Two points can be extracted from this. (1) There are significant differences between normal and tumour cells in the variation of dsb induction. (2) Standard gel electrophoresis is suitable to ...
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