Most cancer treatments—from chemotherapies to engineered immune cells—have a host of side effects, in large part because they affect healthy cells in the body at the same time as targeting tumor cells ...

A group of immune proteins called the inflammasome can help prevent blood stem cells from becoming malignant by removing certain receptors from their surfaces and blocking cancer gene activity, ...

Researchers have developed a new class of antibodies that amplify the immune system’s ability to fight cancer. By clustering immune receptors that normally receive weak signals from tumors, these four ...

C-type lectin receptors (CLRs) are a family of pattern recognition receptors that sense diverse microbial and damage-associated molecular patterns. Many CLRs, like Mincle and Dectin-3, are upregulated ...

IIT Kanpur researchers, led by Professor Arun K Shukla, used cryo-EM to uncover the molecular basis of the atypical immune ...

A new study has uncovered a key mechanism that helps one of the deadliest brain cancers evade the immune system, according to ...

Researchers at the Medical University of Vienna have described a mechanism in metastatic colorectal cancer that has received little attention to date: A key target of existing therapies, the so-called ...

Plants deploy cell-surface and intracellular immune receptors to recognize pathogens. In a comparative analysis of 808 angiosperm genomes, we reveal that during plant adaptation to diverse special ...

You might think of cancer as a mass of rogue cells that grow uncontrollably. But cancer is more organized and strategic than that. Rather, cancer is a tightly controlled cellular neighborhood that can ...

In a paper published in Cell, a USC Stem Cell-led team reports a new way of generating a renewable and expandable supply of the progenitor cells that give rise to macrophages. These immune cells help ...