Analysis of the DNA and proteins of a range of animals has revealed that sperm’s molecular toolkit arose in our single-celled ancestors, perhaps more than a billion years ago ...

New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...

Using Google’s AlphaFold, researchers identified the bundle of three sperm proteins that seem to make sexual reproduction possible. By Elizabeth Preston They’re the original odd couple: One is massive ...

Neil Hunter, a professor in the Department of Microbiology and Molecular Genetics, has discovered a crucial step in how chromosomes stay connected during the development for egg cells and sperm, ...

Groundbreaking research shows that as men age, harmful genetic mutations in sperm become more common—not just from random chance, but because some are naturally favored. Advanced sequencing revealed ...

A genetic mutation that carries a 90% cancer risk has been passed on by an unwitting sperm donor to dozens of children, a Europe-wide investigation has revealed.

Researchers showed how what appears to be a tangle of DNA is actually organized into a structure that coordinates thousands of genes to form a sperm cell. The work, published as two papers in Nature ...