Insulin resistance and β-cell dysfunction are two main molecular bases yet to be further elucidated for type 2 diabetes (T2D). Accumulating evidence indicates that stimulator of interferon genes ...

Objective: To assess the effect of age on glucose metabolism by examining 1) glucose metabolism in young and middle-aged subjects when total or regional adiposity is taken into account and 2) in vitro ...

Prof. Heiko Lickert is the director of the Institute of Diabetes and Regeneration Research at Helmholtz Munich, professor at the Technical University of Munich (TUM), and member of the German Center ...

Homeostasis of metabolism by hormone production is crucial for maintaining physiological integrity, as disbalance can cause severe metabolic disorders such as diabetes mellitus. Here, we show that ...

Amino acids are a major nutrient type for humans and are used as building blocks and a source of energy for cells. Amino acids have also recently been recognized as chemical signals that control cell ...

Hua Medicine Ltd. presented findings from two phase III trials of its first-in-class dual-acting glucokinase activator dorzagliatin that show the drug significantly improved early phase insulin ...

Glucose homeostasis, the appropriate balancing of blood sugar levels, is impaired early in patients who become diabetic, causing life-threatening complications such as kidney failure and heart attacks ...

New research shows your body wants breakfast at sunrise, not sushi at midnight. You might think that when you eat is just a matter of schedule, but your metabolism has its own, far more opinionated ...

Data taken from [22,23]. placebo Fasting serum glucose (%):/DP100 mg: −21.8/DP25 mg: −13.3/DP5 mg−11.7 Significant improvement in oral glucose tolerance test compared with placebo. Urinary glucose ...