BMP, bone morphogenetic protein; BMPR, bone morphogenetic protein receptor; HAMP, hepcidin; HFE, hereditary hemochromatosis protein; HJV, hemojuvelin; Holo-Tf, holo ...
Rusfertide, an investigational, first-in-class, self-injected peptide targeting the hepcidin pathway, shows efficacy in significantly reducing the need for phlebotomy in patients with polycythemia ...
Schematic diagram illustrating the possible mechanism of SMURF1 in serum iron overload (Created with bioRender.com) (IMAGE) Xia & He Publishing Inc. Caption ...
Scientists may have uncovered the root cause of psoriasis, a chronic and sometimes debilitating skin disease that affects 2-3% of the global population. The condition is characterized by red, scaly ...
Rusfertide reduces or eliminates phlebotomy needs in polycythemia vera, improving quality of life and symptom control. The VERIFY trial showed 77% clinical response with rusfertide, compared to 33% in ...
β-Thalassemia is a genetic disorder characterized by reduced or absent synthesis of the beta chains of hemoglobin, leading to ineffective erythropoiesis and severe anemia. Patients with ...
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