Clonal hematopoiesis is a biological process in which a blood stem cell (the population that gives rise to a variety of blood cell types) acquires an advantageous mutation and outgrows neighboring ...

Tumor-infiltrating clonal hematopoiesis increased the risk of disease recurrence or death among patients with cancer. TET2 mutations were the strongest genetic predictor of tumor-infiltrating clonal ...

Please provide your email address to receive an email when new articles are posted on . Clonal hematopoiesis occurred at similar rates among donors and recipients over decades. Findings suggest older ...

Prognostic Value of Neurotrophic Tyrosine Receptor Kinase Gene Fusions in Solid Tumors for Overall Survival: A Systematic Review and Meta-Analysis Recent larger-scale studies of patients with cancer ...

“Clonal hematopoiesis of indeterminate potential is a condition in which a hematopoietic stem cell incurs a somatic mutation that confers a selective advantage to that cell,” explained Dr Jennifer ...

Hyperthermic Intraperitoneal Chemotherapy in Platinum-Sensitive Recurrent Ovarian Cancer: A Randomized Trial on Survival Evaluation (HORSE; MITO-18) Clonal hematopoiesis (CH) has been associated with ...

Please provide your email address to receive an email when new articles are posted on . Clonal hematopoiesis of indeterminate potential, which has been shown to substantially increase risk for blood ...

Clonal hematopoiesis of indeterminate potential (CHIP) is an age-related condition associated with increased mortality among patients with cancer. CHIP mutations with high variant-allele frequencies ...

Telomere shortening is a well-characterized cellular aging mechanism, and short telomere syndromes cause age-related disease. However, whether long telomere length is advantageous is poorly understood ...

Hematopoietic stem cells (HSCs) are multipotent cells that give rise to differentiated blood cells including red blood cells, white blood cells, and platelets. Despite the genetic stability of HSCs, ...

New insights reveal how hidden genetic mutations could be silently fueling heart disease in middle-aged adults, paving the way for personalized prevention strategies. In a recent study published in ...