New research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy type 1 (DM1) and further shows that calcium channel blockers can reverse these ...

Cancer patients often lose excessive amounts of weight. This affects up to 80% of patients and is mainly due to a decrease in ...

The sarcoplasmic reticulum (SR) is a specialised organelle in skeletal muscle fibres that plays a pivotal role in regulating calcium dynamics crucial for muscle contraction and relaxation. Acting as ...

Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium release (CICR) without affecting depolarization-induced calcium release. The ...

The coronary artery supplies blood to the heart. If calcium builds up in the coronary artery, it can lead to coronary artery disease and increase a person’s risk of a heart attack. Calcium is the most ...

Coronary artery calcium scans can offer a more precise estimate of a patient’s chances for major cardiac events. Some cardiologists say it remains underused. By Paula Span A long list of Lynda ...