Recently published results from an evaluation of 1,065 chemical and drug substances using the devTOX quickPredict (devTOXqP) screening platform developed by Stemina Biomarker Discovery, Inc.

Discover expert insights into toxicology screening with mass spectrometry, reducing false results and improving patient ...

This chapter presents a historical perspective of the field of developmental toxicology and then an analysis of various mechanisms by which agents cause developmental toxicity, as currently understood ...

The assessment of developmental toxicity in laboratory mammals is fundamental for evaluating the safety of chemicals, pharmaceuticals and environmental agents that may affect prenatal and postnatal ...

The kidney plays a vital role in maintaining homeostasis within the body by eliminating toxic and superfluous substances in the bloodstream, including waste generated during metabolic processes, ...

Researchers have uncovered the mechanisms that protect the genome from the metabolic toxin formaldehyde in AMeD, a rare congenital disorder of premature aging and myeloid leukemia development. The ...

There is a great need to reduce the cost of developing new pharmaceuticals, now approaching $900 million per drug. About 75% of this cost is attributed to failed drugs. The FDA estimates that a 10% ...

Between 2% and 3% of all live-born infants are estimated to have a major developmental defect identified at birth (ICBD 1991; CDC 1995; Holmes 1997; March of Dimes 1999). The percentage increases ...