Intracellular signaling proteins emerge as a key target in drug development

In a recently published review, a research team led by MedUni Vienna has highlighted a promising new approach to drug ...
Nature

Two-Component Signal Transduction Systems

Two-component signal transduction systems (TCS) are fundamental to the ability of bacteria and certain lower eukaryotes to sense and respond to environmental changes. Typically composed of a sensor ...
Technology Networks

Targeting Intracellular Signaling Proteins for Precision Drug Development

Researchers report a drug discovery strategy using tailor-made cyclic peptides to target β-arrestins, key regulators of ...
The Scientist

Signal Transduction

Edited by: James Kling P.A. Hoodless, T. Haerry, S. Abdollah, M. Stapleton, M.B. O'Connor, L. Attisano, J.L. Wrana, "MADR1, a MAD-related protein that functions in ...
The Scientist

Signal Transduction

There's a whole lot going on in the nucleus of the cell. Genes are transcribed into complementary DNA and then translated to messenger RNA to carry instructions to the protein-building machinery, ...