The shikimate pathway is fundamental for the biosynthesis of aromatic amino acids—tryptophan, tyrosine and phenylalanine—in plants, bacteria and fungi. This pathway, which is absent in mammals, has ...

A subset of natural products, such as polyketides and nonribosomal peptides, is biosynthesized while tethered to a carrier peptide via a thioester linkage. Recently, we reported that the biosyntheses ...

Researchers are building out the repertoire of chemical reactions, using light. They report a method using photobiocatalysis to produce non-canonical (not naturally occurring) amino acids that are ...

A Cleveland Clinic research team recently published an "atlas" of metabolites associated with cardiovascular disease in the European Heart Journal. The novel findings provide key details about the ...

This review illustrates amino acid metabolic reprogramming in breast cancer, highlighting its role in tumor progression and clinical applications, including diagnostic imaging, targeted therapies, ...

In a recent study published in the Nutrients journal, researchers explored the impact of omega 3 (ω-3) and omega 6 (ω-6) fatty acids (FAs) on glucose metabolism. Study: The Effects of Omega 3 and ...