Please provide your email address to receive an email when new articles are posted on . Despite an ever-growing array of potential candidate biomarkers for antineutrophil cytoplasmic ...

US regulators approved avacopan (Tavneos) for a rare immune disorder after receiving additional information to address concerns raised about the drug that were previously discussed at a public meeting ...

Please provide your email address to receive an email when new articles are posted on . “Today is a momentous day in the history of ChemoCentryx; the culmination of decades of effort aimed at offering ...

For patients with autoimmune vasculitides, mortality is on the decline in the U.S. but still remains elevated compared with the general population. These immunological disorders of inflammation of ...

Chronicity on kidney biopsy, not sex, predicts the risk of progression to ESKD at 12 months after diagnosis of AAV in patients with severe kidney disease. Progression to kidney failure at 12 months in ...

The investigators identified 38 patients with ANCA-associated vasculitis. Of these patients, 23 had disease associated with ANCAs to proteinase-3, and 15 had disease associated with myeloperoxidase.

In patients with ANCA-associated vasculitis (AAV), double seropositivity for MPO-ANCA and PR3-ANCA is linked to worse remission rates compared with either AAV type alone. Idiopathic ANCA-associated ...

Autoimmune disease is fundamentally a mystery: whyever should an organism systematically set out to harm itself? Now, researchers at the University of Tsukuba have identified a genetic basis for ...