Fluorescence microscopy holds a pivotal position in cell biology by enabling the visualization of subcellular structures and intercellular interactions 1,2,3,4; however, defocused backgrounds caused ...

The discovery of biofilms dates back to the Dutch microscopist Antonie van Leeuwenhoek, who first observed them on tooth surfaces and described these tiny organisms as “animalcules in the scurf” 1.

A mechanosensitive fluorescent probe visualises and quantifies the mechanical stress on bacterial membranes upon contact with a surface. (Nanowerk News) In natural environments, bacteria rarely live ...

Researchers have developed a new two-photon fluorescence microscope that captures high-speed images of neural activity at cellular resolution. By imaging much faster and with less harm to brain tissue ...

Tunable Bessel beam two-photon fluorescence microscopy enables high-speed volumetric intravital imaging of subcellular dynamics within living mouse brains with fully tunable spatial resolution and ...

Biologists are very interested in how proteins, lipids and other compounds are organized and interact in systems. Very few organizational details can be gained by using standard transmission-based ...

SIMIP enables high-resolution images rich in both chemical and spatial information. A quantum cascade laser (QCL) excites molecular vibrations while a spatial light modulator (SLM) generates striped ...

Recent years have witnessed great advances in applying deep learning to improve fluorescence microscopy imaging. However, enhancing the fidelity of image restoration networks and improving their ...

Researchers have developed a new fluorescence microscopy approach that significantly improves image resolution by acquiring three views of a sample at the same time. Their new method is particularly ...

ST. LOUIS, MO, August 20, 2025 - A team of expert scientists led by Kirk Czymmek, PhD, director of the Advanced Bioimaging Laboratory at the Donald Danforth Plant Science Center and Heather E.

Modern fluorescence microscopy can generate images of living cells as stunning to look at as they are informative to study.

Cryo-electron microscopy (cryo-EM) can help scientists determine the three-dimensional structure of proteins in unprecedented detail. Jacques Dubochet, former group leader at EMBL, shared the 2017 ...