San Francisco 49ers star running back Christian McCaffrey was added to the team’s injury report Saturday due to a back injury.

The San Francisco 49ers have placed receiver Brandon Aiyuk on the reserve/left squad list, making him ineligible to return from a knee injury this season.

A recharged San Francisco 49ers squad returns from a late season break with renewed momentum as quarterback Brock Purdy guides a push toward an NFC West shake-up.

San Francisco 49ers quarterback Brock Purdy is officially out for Sunday's game against the Tampa Bay Buccaneers due to the toe injury that has caused him to miss multiple games already this season. Backup quarterback Mac Jones is listed as questionable ...

The San Francisco 49ers have had a strong season while overcoming impactful injuries, but Kyle Shanahan says it isn't the team he's most proud of.

Riding a three-game winning streak into the Bye Week had to have put the San Francisco 49ers on cloud nine. But what probably put them there the most was their

Los 49ers de San Francisco colocaron al receptor Brandon Aiyuk en la lista de reserva, lo que lo hace inelegible para regresar de una lesión de rodilla esta temporada.

The San Francisco 49ers have been great after their bye week since Kyle Shanahan took over, but they struggled in 2024.