Lionel Messi departed Inter Miami's matchup with Necaxa in the 2025 Leagues Cup on Saturday with a hamstring injury, head coach Javier Mascherano told reporters after the team's win on penalties.

Messi appeared to get tripped going for the ball in the eighth minute, fell to the ground and slammed his fist in frustration before walking toward midfield as play continued.

The Herons have been reliant on their Argentine No. 10, and he pushed them to the last 16 of the Club World Cup, taking down Porto in the process. With Segovia and Tadeo Allende, there are other players who can step up to assist Luis Suarez in the attack, but Mascherano will need to determine the best setup if their star misses any time.